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Ignacio Fernández Mata

Ignacio Fernández Mata


Acting Instructor, Department of Neurology. University of Washington, EE.UU.


Máster en Trastornos del Movimiento

Universidad de Murcia

Biographical Sketch


2001-2003       Research Assistant , Molecular genetics Department in Hospital Universitario Central de Asturias, SPAIN. Supervisors: Dr. E. Coto and V. Alvarez
2004- March 2006       Predoctoral Graduate Student, Department of Neurosciences, Mayo Clinic, Jacksonville, FL. Supervisor: Dr. Matthew Farrer

September 2006- March2011  Postdoctoral Fellowship, Department of Neurology, University of Washington, Seattle. Supervisor Dr. Cyrus Zabetian

April 2011- present                 Acting Instructor, Department of Neurology, University of Washington

Special National International responsibilites

2005-present                          Head of the Latin American Research consortium on the Genetics of Parkinson’s Disease (LARGE-PD)

Teaching responsibilities

11/03                  Course of basic molecular techniques in the genetic diagnosis, Hospital Universitario Central de Asturias
05/11                  Lecture at the University of Washington (invited by Dr Edwards; Dept of Epidemiology) graduate level course PHG518 (Computer Applications in Genetic epidemiology) entitled: “Genetics of Parkinson’s disease: Past and Future” (2hrs)
10/11                  Lecture at the Universidad Peruana Cayetano Heredia for the Programa Integrado con Certificacion progresiva de diplomados y Maestria en genetica humana entitled: “Introduccion a la genética aplicada en medicina. Estudios de Asociacion de genoma completo (GWAS): comienzo de la medicina personalizada” (4 hrs)
09/12                  Masters Committee Member to Leonardo Bonilla Ramirez, Neurosciences Dept., University of Antioquia, Colombia
2010-2013          Mentor to Mario Reynaldo Cornejo Olivas (Fogarty Scholar), Instituto Nacional de Ciencias Neurologicas, Lima, Peru
2012-present      Masters thesis external advisor to Mario Reynaldo Cornejo Olivas, Human Genetics Dept., Peruvian University Cayetano Heredia, Peru
05/13                  UW Neurology Grand Rounds: “ An update in Parkinson’s disease genetics: Applications of Next-Generation sequencing to Neurology”
During the above training periods I have become familiar with a large range of molecular biology and cell biology techniques:
·         Expertise in genetic screening, including techniques such as SSCP (Single Strand Conformation Polymorphism) and direct sequencing. These involve the design of PCR primers, optimization of conditions and data analysis with software packages such as Sequencher and SeqScape (ABI), and Phred-Phrap (UW) in a different set of machines as ABI310, ABI3100, ABI3730. I am also competent in the use of these systems to do semiquantification analysis. Also familiar with the maintenance of this machines.
·         Experience in the use of the ABI7900 system and the SDS software for allelic discrimination by Taqman assays. I am also familiar with the use of this equipment to do Real time and quantification measures.
·         Competent in the culturing and analysis of primary neurons; as part of this I have also had the Mayo animal handling training and have experience of some breeding protocols. In addition have also had experience with immunohistochemistry analysis of human and mouse tissue and I have become familiar with AAV viral technology.
·         Familiar with protein analysis techniques including immunoblotting.
·         Experience in using web resources such as UCSC Genome Browser, Vista tools, genetic databases (such as NCBI, Genome Variation Server), etc.
·         Use of Microsoft Office (Excel, Power Point, Word), and several adobe programs such as adobe illustrator.
·         Use of statistical packages such as SPSS, STATA, Hplus, PLINK, and other bioinformatics tools such as haploview.